The MLN8054 Diaries
Desk one summarizes the observed DLTs by cohort. Somnolence, which solved in all but a single patient, was the one DLT for MLN8054 offered devoid of methylphenidate or modafinil. The onset of somnolence and its severity usually were being correlated with dose and Cmax. Due to the fact somnolence was considered relevant to Cmax, the dosing routine w